Unravelling var complexity: relationship between dblα types and var genes in plasmodium falciparum

HIGHLIGHTS

  • who: Mun Hua Tan and colleagues from the Mahidol University have published the paper: Unravelling var complexity: Relationship between DBLu03b1 types and var genes in Plasmodium falciparum, in the Journal: (JOURNAL)
  • what: In all four study sites, DBLa-var relationships were shown to be predominantly specific (i.e., 1-to-1) with much smaller major surface antigen of the blood stages is known as P. falciparum erythrocyte membrane-1 protein (PfEMP1) encoded by the var multigene family. The authors show that the use of DBLa types to estimate var diversity is limited to the scale . . .

     

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