HIGHLIGHTS
- who: Felipe Silva de Franu00e7a and Denise V. Tambourgi from the Lawson Health Research Institute, Canada University of Su00e3o Paulo, Brazil have published the article: Hyaluronan breakdown by snake venom hyaluronidases: From toxins delivery to immunopathology, in the Journal: (JOURNAL)
SUMMARY
LMW-HA, by promoting an increase in inflammation-related gene_expression, polarizes macrophages toward the M1 phenotype, making them highly inflammatory. Frontiers in Immunology frontiersin.org 10.3389/fimmu.2023.1125899 reactions in_vivo. LMW-HA elicits functional maturation of human and mouse DCs, as detected by the increase of MHC-II and B7 . . .
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