HIGHLIGHTS
- who: Maura Rojas-Pirela and colleagues from the Instituto de Biologu00eda, Facultad de Ciencias, Pontificia Universidad Catu00f3lica de Valparau00edso have published the paper: Antimicrobial Peptides (AMPs): Potential Therapeutic Strategy against Trypanosomiases?, in the Journal: Biomolecules 2023, 599 of /2023/
- what: AMPs are small peptides that have been shown to possess activity against different strains of T. cruzi and T. brucei, exerting their specific effect through different mechanisms such as rupture of the plasma_membrane, alteration of calcium homeostasis, inhibition of some metabolic pathways, disturbance of organelles, and activation of various cell death pathways.
SUMMARY . . .
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