Molecular modeling and potential ca2+ channel blocker activity of diphenylmethoxypiperidine derivatives

HIGHLIGHTS

  • who: Victor M. Pulgar et al. from the Department of Pharmaceutical and Clinical Sciences, College of Pharmacy and Health Sciences, Campbell University, Buies Creek, NC, USA have published the Article: Molecular Modeling and Potential Ca2+ Channel Blocker Activity of Diphenylmethoxypiperidine Derivatives, in the Journal: Chemistry 2023, 5, FOR PEER REVIEW of /2023/
  • what: Molecular interactions with the calcium channel subunit Cav1.1 may explain the ability of 4-diphenylmethoxy-1-methylpiperidine derivatives to partially inhibit Ca2+ -dependent contractions.
  • how: For the modelling studies the authors used 1-methylpiperidine 2a 2b and 4a were . . .

     

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