The association of lipid transfer protein vps13a with endosomes is mediated by sorting nexin snx5

HIGHLIGHTS

  • who: Alba Tornero-Eu0301cija and colleagues from the (UNIVERSITY) have published the paper: The association of lipid transfer protein VPS13A with endosomes is mediated by sorting nexin SNX5, in the Journal: (JOURNAL)
  • what: This model has been proposed for the yeast-sorting nexin SNX5 is an endosomal adaptor of VPS13A Tornero-Eu0301cija et_al Ypt35 and the PI3P-binding APT1 domain of Vps13, which together appear to be required for Vps13 recruitment to endosomal and vacuolar membranes (Kolakowski et al, 2020).
  • how: LexA-VPS13A fusion containing the VAB domain was tested for interaction with . . .

     

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