HIGHLIGHTS
SUMMARY
This discovery focused the attention of the research community onto the idea that a "concealed" antigen could be used to elicit a robust immune_response and from there the question of wheter both "exposed" and "concealed" antigens present the requisites needed to be included in a potential tick vaccine, emerged. The definition of "exposed" and "concealed" antigens and the characterization of their "mode of action", regarding host immune_response is presented. If "exposed" antigens naturally elicit a host immune_response through the action of dendritic cells, which process and present these antigens to T lymphocytes, priming a . . .
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