Radiation-induced nephropathy in the murine model is ameliorated by targeting heparanase

HIGHLIGHTS

• who: Alexia Abecassis and colleagues from the Sharett Institute of Oncology, Hadassah-Hebrew University Medical Center, Jerusalem , have published the research: Radiation-Induced Nephropathy in the Murine Model Is Ameliorated by Targeting Heparanase, in the Journal: Biomedicines 2023, 11, x FOR PEER REVIEW of /2023/
• what: The authors report that heparanase an extracellular matrixdegrading enzyme is a promising candidate for preventing radiation nephropathy.

SUMMARY

IR induces the expression of heparanase in cells of kidney origin in_vivo. IR upregulates renal heparanase expression in_vivo. The above findings promp an examination of the effect . . .

 



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