HIGHLIGHTS
- who: Christine Gaboriaud from the Alpes, Grenoble, France Brunel University London have published the research: Complement System and Alarmin HMGB1 Crosstalk: For Better or Worse, in the Journal: (JOURNAL)
- what: Among similarities between the two systems, the authors aim to illustrate amplification mechanisms as well as the plethora of receptors and signaling pathways involved, their effect thus depending on the local tissues and environment. The modular assembly of the smallest (HMGB1) and largest (C1q) proteins in the focus of this review are presented in Figure 1. Since HMGB1 and the complement proteins in the focus . . .
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