Driver gene alterations in malignant progression of gastric cancer

HIGHLIGHTS

  • who: Yuanqiang Dong from the Department of General Surgery, Huashan Hospital, Fudan University, Shanghai, China have published the Article: Driver Gene Alterations in Malignant Progression of Gastric Cancer, in the Journal: (JOURNAL)
  • what: The authors aimed to identify driver gene alterations and their correlation with immune infiltration levels and the subsequent signaling pathways that drive the progression of GC to develop more effective therapies. The analysis showed that signature 6 was mainly associated with the GC spectrum of mutations because of the lack of DNA mismatch repair and signature 17 . The study provides several insights . . .

     

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