Aqp5 complements lgr5 to determine the fates of gastric cancer stem cells through regulating ulk1 ubiquitination

HIGHLIGHTS

  • who: Rou Zhao from the Department of Laboratory Medicine, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining, Shandong, Peopleu2019s Republic of China have published the research: AQP5 complements LGR5 to determine the fates of gastric cancer stem cells through regulating ULK1 ubiquitination, in the Journal: (JOURNAL)
  • what: The authors report the identification and validation of AQP5 as a potentially specific surface marker of GC-CSCs. Fourth, this study reveals a previously unknown mechanism by which AQP5 regulates the autophagy and stemness of GC-CSCs. The authors demonstrate novel biological functions of AQP5 in . . .

     

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