HIGHLIGHTS
- who: Yue Yu from the School of Medicine, Shenzhen Campus of Sun Yat-sen University, Shenzhen, China have published the article: H3K27me3-H3K4me1 transition at bivalent promoters instructs lineage specification in development, in the Journal: (JOURNAL)
- what: The authors report that in the process of lineage differentiation promoters undergo H3K27me3-H3K4me1 transition the loss of H3K27me3 accompanies by bimodal pattern loss or unimodal pattern enrichment of H3K4me1. In current study, the authors reported that H3K4me1 in combination with H3K4me3 considerably distinguish bivalent and non-bivalent promoter CGIs in ESCs. This study provided more insights into . . .
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