Traditional chinese medicine formula jian pi tiao gan yin reduces obesity in mice by modulating the gut microbiota and fecal metabolism

HIGHLIGHTS

SUMMARY

The intestinal flora exerted a vital regulatory effect on obesity pathophysiology and related diseases through the regulation of intestinal appetitestimulating hormone, changes in insulin resistance (IR), nutrient digestion, energy regulation, glucose metabolism, and lipid metabolism. Chinese herbal medicines have been shown to regulate the composition of intestinal flora, fecal short-chain fatty_acids (SCFAs), intestine barrier functions, and intestinal inflammatory events. Ltd); the Group HFD (n=10), fed an HFD (XTHF60-1 diet, 60.65 kcal% fat, Jiangsu Synergy Medicine Bioengineering Co., Ltd); and_(3) the Group JPTGY (n=10), HFD supplied with JPTGY. The . . .

 



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