Pyk2 senses calcium through a disordered dimerization and calmodulin-binding element

HIGHLIGHTS

• who: Afaque A. Momin from the Bioscience Research Center (CBRC), King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia have published the research: PYK2 senses calcium through a disordered dimerization and calmodulin-binding element, in the Journal: (JOURNAL) of 14/Dec/2021
• what: The authors used a multidisciplinary approach to determine the molecular mechanism of Ca2+ sensing by PYK2. The authors demonstrated that Ca2+ can control PYK2 by reinforcing an association between CaM and a PYK2 linker region located between its kinase and FAT domains. The authors propose that PYK2 dimerisation is based . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.