Listeria-vectored multi-antigenic tuberculosis vaccine protects c57bl/6 and balb/c mice and guinea pigs against mycobacterium tuberculosis challenge

HIGHLIGHTS

• who: Qingmei Jia from the Department University of have published the Article: Listeria-vectored multi-antigenic tuberculosis vaccine protects C57BL/6 and BALB/c mice and guinea pigs against Mycobacterium tuberculosis challenge, in the Journal: (JOURNAL)
• what: The authors investigate the immunogenicity and efficacy of rLm5Ag and rLm9Ag as standalone vaccines in three animal models of pulmonary TB-inbred C57BL/6 and and outbred Hartley guinea pigs. In C57BL/6 and the authors show that homologous priming-boosting with rLm5Ag and rLm9Ag vaccines induces antigen-specific CD4+ and CD8+ T cell immune responses and protective . . .
  

   

  

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