Listeria-based immunotherapy directed against cd105 exerts anti-angiogenic and anti-tumor efficacy in renal cell carcinoma

HIGHLIGHTS

• who: Mariam Oladejo from the University of Florida, United States have published the Article: Listeria-based immunotherapy directed against CD105 exerts anti-angiogenic and anti-tumor efficacy in renal cell carcinoma, in the Journal: (JOURNAL)
• what: The authors show the safety and efficacy of targeting tumor vasculature-associated endothelial and tumor cell-expressed CD105 by an Lm-based vaccine, Lm-LLO-CD105A, in both subcutaneous and orthotopic models of RCC. The authors propose that targeting CD105 with an Lm-based vaccine may be a promising strategy for improving survival in patients with RCC.
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