Mapping human disease-associated enzymes into reactome allows characterization of disease groups and their interactions

HIGHLIGHTS

• who: Castrense Savojardo from the University of have published the article: Mapping human disease-associated enzymes into Reactome allows characterization of disease groups and their interactions, in the Journal: Scientific Reports Scientific Reports of 05/04/2022
• what: When the authors focus on the disease-enzyme-Reactome association the authors can dissect this interaction-space and derive useful categorizations detailed in the following.

SUMMARY

The majority of diseases univocally map on one root only (Fig 6), while the remaining 1041 are associated to more than one root, with the extreme cases . . .

 



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