A zebrafish model of growth hormone insensitivity syndrome with immune dysregulation 1 (ghisid1)

HIGHLIGHTS

  • who: Somayyeh Heidary from the School Medicine, Deakin University, Pigdons Road, Geelong, VIC, Australia have published the paper: A zebrafish model of growth hormone insensitivity syndrome with immune dysregulation 1 (GHISID1), in the Journal: (JOURNAL)

SUMMARY

    This identified the mutant allele mdu022, which represents a 47 bp insertion that results in the addition of five de novo amino_acid residues after T155 followed by a stop codon (Fig 1G), resulting in a large truncation of Stat5.1 similar to that observed with the human STAT5B R152X LOF mutation. B Alignment of human STAT5B with . . .

     

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