Adverse drug reactions and associated patient characteristics in older community-dwelling adults: a 6-year prospective cohort study

HIGHLIGHTS

• who: Ann S Doherty and collaborators from the As older people are living longer, often with multimorbidity, caring for this population is becoming increasingly complex, and much of this care occurs in primary care [1, ]For the GP, estimating the benefits and harms of a medication in an older person is particularly challenging as comorbidities, concurrent medications, pharmacokinetics, and pharmacodynamics can all impact the clinical outcome [3, ]. The prevalence of polypharmacy, defined as u2265, regular prescribed medications, is increasing, particularly among older people [5, ]. Polypharmacy is the primary risk factor for adverse drug reactions (ADRs), one type . . .
  

   

  

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