Mitochondrial base editing: recent advances towards therapeutic opportunities

HIGHLIGHTS

• who: Bibekananda Kar and colleagues from the Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, USA have published the paper: Mitochondrial Base Editing: Recent Advances towards Therapeutic Opportunities, in the Journal: (JOURNAL) of 15/01/2023
• what: The authors focused on recent advancements in the field of mitochondrial base editing, which holds the potential to treat diseases caused by pathogenic mtDNA point mutations in both heteroplasmic and homoplasmic contexts without the risk for mtDNA depletion . In their report of a DdCBE library for the ablation of all protein-coding genes in mouse mtDNA . . .
  

   

  

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