The effects of device-based cardiac contractility modulation therapy on left ventricle global longitudinal strain and myocardial mechano-energetic efficiency in patients with heart failure with reduced ejection fraction

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SUMMARY

The effects of CCM on the MEE of patients with HFrEF are still unknown; therefore, in this study, the authors evaluate whether CCM therapy can improve the MEE of patients with HFrEF. The following exclusion criteria were used: acute coronary syndrome in the previous three months, cardiac resynchronization therapy device implantation in the previous 12 months, absence of aortic stenosis or left ventricular outflow tract (LVOT) obstruction, non-target dose of OMT for HFrEF, end-stage kidney disease required renal replacement therapy. In this study, for the first time, the authors demonstrate that left . . .

 



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