HIGHLIGHTS
- who: John Santelices et al. from the PharmCADD, Republic of Korea The University of Manchester have published the research: USP8 inhibition regulates autophagy flux and controls Salmonella infection, in the Journal: (JOURNAL)
- what: The experiment described above was repeated, but instead of immunopurification, crude lysates (control samples containing no Ub-VS-HA labeling), and probe-reacted deubiquitinases (shown by increased molecular weight upon Ub-VS-HA binding) were visualized by using western blotting. This study determined that USP8 is downregulated in macrophages during Salmonella infection but not during Yersinia infection, indicating that the regulation of . . .
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