HIGHLIGHTS
- who: . and colleagues from the Fudan University, China have published the article: Population pharmacokinetics of nalbuphine in patients undergoing general anesthesia surgery, in the Journal: (JOURNAL) of 23/Dec/2022
- what: The aim of this study was to build a population pharmacokinetics (PopPK) model of nalbuphine and to estimate the suitability of bodyweight or fixed dosage regimen. In this study, a total of 458 plasma concentrations were collected from 48 patients. In this study, fixed dose regimen (15 mg) was explored in patients undergoing anesthesia surgery based on published literature (Cai et_al, 2011; He et_al . . .
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