A novel toxoplasma gondii tggt1_316290 mrna-lnp vaccine elicits protective immune response against toxoplasmosis in mice

HIGHLIGHTS

  • who: ufeffDanufeff ufeffLiufeff from the Medical University of Vienna, Austria have published the research: A novel ufeffToxoplasma gondiiufeff TGGT1_316290 mRNA-LNP vaccine elicits protective immune response against toxoplasmosis in mice, in the Journal: (JOURNAL)
  • how: Bioinformatics data showed that TG290 had a higher epitope score for linear B cells than SAG1 and a lower predicted IC50 value than SAG1 theoretically showing that TG290 is a promising vaccine candidate.

SUMMARY

    Toxoplasma gondii (T. gondii) is an obligate intracellular parasite that threatens one-third of the world`s population (Almeria et_al, 2021; Smith . . .

     

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