HIGHLIGHTS
SUMMARY
The prefrontal cortex (PFC) is a brain region thought to play an important role in alcohol seeking behavior (Stephens and Duka, 2008; Crews and Boettiger, 2009; Koob and Volkow, 2010; Willcocks and McNally, 2013; Gass et_al, 2014; Brown et_al, 2016; Cannady et_al, 2017; Palombo et_al, 2017). Prior studies have documented the important role of PFC excitatory pyramidal neurons in the reinforcing effects of alcohol (Willcocks and McNally, 2013; Gass et_al, 2014; Brown et_al, 2016; Cannady et_al, 2017; Palombo et_al, 2017). In rodents, the excitatory neurons in the prelimbic cortex mediate cue-mediated ethanol seeking . . .
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