HIGHLIGHTS
SUMMARY
"The immediate utility of an organic structure often says nothing at all about the reason for its being."-Richard Lewontin and Stephen Jay Gould The term RNA interference (RNAi) refers to a range of molecular processes that use a small RNA fragment as a guide to target specific nucleic_acid sequences and regulate gene_expression. The prevailing view is that RNAi evolved as a defense response against transposable_elements (TEs) and RNA viruses in eukaryotes. Viewing RNAi systems as having roles in both defense and regulation can reveal new avenues through which to understand their evolutionary origins . . .
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