HIGHLIGHTS
- who: Elio Haroun from the (UNIVERSITY) have published the paper: Intestinal barrier functions in hematologic and oncologic diseases, in the Journal: (JOURNAL)
- what: There is now abundance of evidence to implicate the roles of increased intestinal permeability in various systemic disease states.
SUMMARY
Contents into the systemic circulation, GI mucosal epithelium also regulates adaptive immune_responses. Depletion of the mucus layer due to dysbiosis brings microbiota to close proximity of the epithelial_cells. Pattern recognition receptors (PRRs) such as Toll-like receptors (TLRs) expressed on epithelial_cells interact with microbiota-derived pathogen-associatedmolecular patterns . . .
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