HIGHLIGHTS
SUMMARY
Mitochondria own a circular 16.6-kb DNA genome encoding two ribosomal RNAs, 22 transfer RNAs, and 13 open_reading_frames for electron_transport_chain complex subunits. During energy production, mitochondria participate in numerous metabolic reactions, such as tricarboxylic_acid_cycle and oxidative_phosphorylation, and some intermediate metabolites are indispensable for cell proliferation and survival, but some by-products, Frontiers in Oncology frontiersin.org 10.3389/fonc.2023.1145379 competitively replaced YB1 original bound transcripts and reduced their half-life time, resulting in cancer cell inhibition and mitochondrial dysfunction. such as reactive oxygen species, are harmful for most cells. YB1 inhibited . . .
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