Biomimetic cultivation of atrial tissue slices as novel platform for in-vitro atrial arrhythmia studies

HIGHLIGHTS

  • who: Jorik H. Amesz from the Erasmus University have published the article: Biomimetic cultivation of atrial tissue slices as novel platform for in-vitro atrial arrhythmia studies, in the Journal: Scientific Reports Scientific Reports
  • what: This model shows high in-vivo representativeness, due to the use of human specimen which maintain 3D architecture with intact cellular interconnections and cell-cell communication.

SUMMARY

    Isoprenaline enhancement (1 µM) was needed to maintain sufficient contractions in the LMS. An important aspect of LMS is their multicellularity with retained cardiac cellular composition, architecture and physiology . . .

     

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