Mir449 protects airway regeneration by controlling aurka/hdac6-mediated ciliary disassembly

HIGHLIGHTS

  • who: Merit Wildung and collaborators from the Molecular Oncology, University Medical Center Goettingen, Goettingen, Germany have published the paper: miR449 Protects Airway Regeneration by Controlling AURKA/HDAC6-Mediated Ciliary Disassembly, in the Journal: (JOURNAL)
  • what: The authors report for the first time a connection between miR449 and cilia-related processes in COPD patients. The authors focused the following analyses on investigating the role of miR449 in ciliated airway epithelia regeneration. In this context, the authors show the positive effect of 10 of 28 miR449 on bronchial regeneration. Ciliary Homeostasis Next, the authors aimed to investigate . . .

     

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