Usp1 modulates hepatocellular carcinoma progression via the hippo/taz axis

HIGHLIGHTS

  • who: Dongyi Liu from the (UNIVERSITY) have published the paper: USP1 modulates hepatocellular carcinoma progression via the Hippo/TAZ axis, in the Journal: (JOURNAL) of 22/Nov/2022
  • what: The study proposed a regulatory link between USP1 and the Hippo/TAZ axis and a promising target for treating HCC. The research showed that USP1 depletion specifically Cell Death and Disease 14:264 increased K11-linked ubiquitination (Fig 6C). The authors propose that pharmaceutically targeting USP1 function or inhibiting USP1 expression may be effective in suppressing Hippo/TAZ-driven hepatocellular carcinoma.
  • how: The small . . .

     

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