Als-linked tdp-43 mutations interfere with the recruitment of rna recognition motifs to g-quadruplex rna

HIGHLIGHTS

• who: Akira Ishiguro from the Research Center forHosei University, Midoriu2011cho, u201111u201115, Koganei, Tokyo, u20110003, Japan have published the research work: ALS-linked TDP-43 mutations interfere with the recruitment of RNA recognition motifs to G-quadruplex RNA, in the Journal: Scientific Reports Scientific Reports
• how: The authors used these G4-RNAs and TDP-43 proteins that had the G287S or M337V mutations and the lowest G4-RNA binding properties (Fig 1A).

SUMMARY

Using PSD-95 (postsynaptic density protein 95) and CaMKIIα (calcium/calmodulin-dependent protein kinase II alpha subunit), two dendritic . . .

 



If you want to have access to all the content you need to log in!

Thanks :)

Username or Email

Password

Remember me

Lost your password?

If you don't have an account, you can create one here.