Nanobodies for the early detection of ovarian cancer

HIGHLIGHTS

  • who: Lan-Huong Tran and colleagues from the Biomolecule Design Group, Institute for Materials Research (IMO-IMOMEC), Hasselt University have published the research work: Nanobodies for the Early Detection of Ovarian Cancer, in the Journal: (JOURNAL)
  • what: In this study nanobodies targeting the cancer biomarkers human epididymis protein 4 (HE4) secretory leukocyte protease inhibitor (SLPI) and progranulin (PGRN) were evaluated regarding their expression levels in bacterial systems epitope binning and antigen-binding affinity by enzyme-linked immunosorbent assay and surface plasmon resonance. The LOD values obtained in this study were signifi80.7 pM that was . . .

     

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