Visualizing pyrazinamide action by live single-cell imaging of phagosome acidification and mycobacterium tuberculosis ph homeostasis

HIGHLIGHTS

  • who: Maximiliano G. Gutierrez and collaborators from the College Department of Biochemistry, University of Lausanne, Epalinges, Switzerland have published the research work: Visualizing Pyrazinamide Action by Live Single-Cell Imaging of Phagosome Acidification and Mycobacterium tuberculosis pH Homeostasis, in the Journal: (JOURNAL) of 23/08/2022
  • what: The authors describe a live dualimaging approach to monitor host subcellular and intrabacterial By combining this approach with pharmacological and genetic perturbations the authors show that can maintain its intracellular independently of the surrounding in human macrophages. By live-cell imaging and tracking of M. tuberculosis bacterial populations . . .

     

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