Hexahydro-1,3,5-trinitro-1,3,5-triazine (rdx) causes seizure activity in larval zebrafish via antagonism of γ-aminobutyric acid type a receptor α1β2γ2

HIGHLIGHTS

• who: Paige C. Mundy from the Department of Molecular Biosciences, Davis School of Veterinary Medicine, University of California, Veterinary Medicine Drive, Davis, CA, USA have published the research work: Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) causes seizure activity in larval zebrafish via antagonism of u03b3-aminobutyric acid type A receptor u03b11u03b22u03b32, in the Journal: (JOURNAL)
• how: To address this data gap the authors developed an in_vivo model for RDX-induced seizures using an exposure paradigm that yields consistent and predictable behavioral and electrographic seizures in 5 dpf zebrafish larvae.
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