Lung tissue shows divergent gene expression between chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis

HIGHLIGHTS

  • who: Auyon J. Ghosh from the 2115, USA have published the research work: Lung tissue shows divergent gene expression between chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis, in the Journal: (JOURNAL)
  • what: The authors focused on cell types previously associated with COPD and IPF . The authors report results from a large sample size of lung tissue RNA sequencing from subjects with COPD and IPF. The authors show that this gene signature is associated with reduced lung function in both COPD and IPF, suggesting the presence of a common inflammatory subtype with increased disease severity . . .

     

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