Genome-wide mapping of individual replication fork velocities using nanopore sequencing

HIGHLIGHTS

  • who: Bertrand Theulot from the Ecole Normale PSL, rue d`Ulm, Paris, France have published the article: Genome-wide mapping of individual replication fork velocities using nanopore sequencing, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: The authors selected among the >125,000 individual forks detected by NFS in BT1 cells grown at 30 u00b0C those for which the chase was long enough (>2.5 kb), fitted the u224890,000 forks meeting this criterion using the model described in the u2018Simulation of BrdU level` section and the speed measured by NFS, and extracted fork parameters . . .

     

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