Stearoyl-coa desaturases1 accelerates non-small cell lung cancer metastasis by promoting aromatase expression to improve estrogen synthesis

HIGHLIGHTS

  • who: Jiaping Chen et al. from the Department of Thoracic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China have published the research: Stearoyl-CoA Desaturases1 Accelerates Non-Small Cell Lung Cancer Metastasis by Promoting Aromatase Expression to Improve Estrogen Synthesis, in the Journal: (JOURNAL)
  • what: The authors demonstrated that the SCD1-activated Wnt pathway is an important regulator of CYP19A1 and an important source of local estrogen in NSCLC. 14 of 20 This study shows that SCD1 is a promising target for inhibiting NSCLC metastasis.
  • how: The . . .

     

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