Recognition of a clickable abasic site analog by dna polymerases and dna repair enzymes

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SUMMARY

    Incorporation of a normal dNMP by a DNA_polymerase followed ferred to as an AP lyase activity. Incorporation of a normal dNMP by a DNA_polymerase by ligationbycomplete roundthe of BER. not repaired, AP sites are more harmful followed ligation the complete roundIf of BER. It was of interest to investigate interaction this clickable abasic site an- with DNA_polymerases and BER enzymes. alog with DNA_polymerases and BER enzymes. DNA_polymerase I has a specialized in completing the bacterial lagging DNA_polymerase I has a specialized role role in completing the bacterial lagging_strand strand synthesis and is the major . . .

     

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