Detecting variation in ploidy within and between genomes

HIGHLIGHTS

  • who: Peter et al. from the (UNIVERSITY) have published the Article: Detecting variation in ploidy within and between genomes, in the Journal: (JOURNAL) of 01/07/2021

SUMMARY

    Recommendation Soraggi et_al describe HMMploidy, a statistical method that takes DNA sequencing data as input and uses a hidden Markov model to estimate ploidy. The method allows ploidy to vary not only between individuals, but also between and even within chromosomes. HMMploidy estimates genotypes and ploidy simultaneously, with a separate estimate for each genome. The genome is divided into a series of non-overlapping windows . . .

     

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