Mendelian randomisation confirms the role of y-chromosome loss in alzheimer’s disease aetiopathogenesis in men

HIGHLIGHTS

• who: Pablo Garcu00eda-Gonzu00e1lez et al. from the Catalunya, Barcelona, Spain, Centro Nacional Genotipado (CEGEN-PRB3-ISCIII), Universidade have published the research: Mendelian Randomisation Confirms the Role of Y-Chromosome Loss in Alzheimeru2019s Disease Aetiopathogenesis in Men, in the Journal: (JOURNAL)
• how: The effect size increased when the authors calculated the model exclusively using conversion to AD but did not reach statistical significance (HR=2.05 p=0.19). mLOY6calls Int. The authors removed samples with a high heterozygosity 13 of 17 14 of 17 MCI-EADB) the authors introduced a dichotomous variable in the . . .
  

   

  

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