G-protein coupled receptor 19 (gpr19) knockout mice display sex-dependent metabolic dysfunction

HIGHLIGHTS

• who: Bellina A. S. Mushala from the Vascular Medicine InstituteUniversity of have published the research work: G-protein coupled receptor 19 (GPR19) knockout mice display sex-dependent metabolic dysfunction, in the Journal: Scientific Reports Scientific Reports
• what: The authors demonstrate for the first time a role for the orphan G-protein coupled receptor, GPR19, in the regulation of systemic metabolic homeostasis in diet-induced obesity. Using a novel whole-body Gpr19-/- mouse model, the authors show that GPR19 deficiency induces a shift in whole-body energy metabolism by increasing energy expenditure and decreasing glucose disposal . . .
  

   

  

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