HIGHLIGHTS
- who: Siyuan Weng from the (UNIVERSITY) have published the Article: Epigenetically regulated gene expression profiles decipher four molecular subtypes with prognostic and therapeutic implications in gastric cancer, in the Journal: (JOURNAL)
- what: This study demonstrated the co-regulatory mechanism of miRNA expression and DNA methylation. (2) Although the authors did not observe a significant negative correlation phenomenon similar to CpG-mRNA among miRNA-mRNA pairs (Additional file 1: Fig S1A), the negatively correlated miRNA-mRNA pairs were only retained for the following reasons: (i) generally, miRNAs negatively regulate downstream gene_expression.
- how: Comprehensive validation . . .
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