Delayed generation of functional virus-specific circulating t follicular helper cells correlates with severe covid-19

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  • who: Meng Yu from the Laboratory analysesb, c have published the article: Delayed generation of functional virus-specific circulating T follicular helper cells correlates with severe COVID-19, in the Journal: (JOURNAL) of 20/07/2022
  • what: The authors observed a delayed appearance of activated and SARS-CoV-2-specific cTfh but not non-cTfh cells in severe compared to mild COVID-19 patients during early infection (less than 2 weeks after symptom onset). The authors focus on cTfh cells, which originated from lymph nodes16,17 and display clonal and developmental overlap with GC Tfh . . .

     

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