HIGHLIGHTS
- who: Yael Aylon from the (UNIVERSITY) have published the article: Breast cancer plasticity is restricted by a LATS1-NCOR1 repressive axis, in the Journal: (JOURNAL) of 12/01/2022
- what: The authors propose that by enforcing rigorous silencing of repressed genes, the LATS1-NCOR1 axis maintains luminal cell identity and restricts breast cancer progression. The authors report the use of single-cell profiling to generate a high throughput multi-parametric analysis of cellular epigenetic heterogeneity in mammary tumors. Specifically, the authors report that LATS1 maintains luminal cell identity by associating with NCOR1 to secure the . . .
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