HIGHLIGHTS
- who: Vera-Marie E. Dunlock from the Radboud Institute Radboud University the Netherlands have published the article: Tetraspanin CD53 controls Tu00a0cell immunity through regulation of CD45RO stability, mobility, and function, in the Journal: (JOURNAL) of June/28,/2022
- what: The authors show that CD45RO stability and function in T_cells is specifically regulated by the tetraspanin CD53. The authors report a molecular interaction between CD45 and CD53 on the immune cell surface. CD45 isoform switching occurs during normal T_cell activation, yet the purpose of this process remains largely unclear. Although the authors show that CD53 affects . . .
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