Sars-cov-2 infection induces dna damage, through chk1 degradation and impaired 53bp1 recruitment, and cellular senescence

HIGHLIGHTS

• who: Ubaldo Gioia from the (UNIVERSITY) have published the paper: SARS-CoV-2 infection induces DNA damage, through CHK1 degradation and impaired 53BP1 recruitment, and cellular senescence, in the Journal: (JOURNAL) of 17/Dec/2021
• what: The authors show that SARS-CoV-2 causes DNA damage and elicits an altered DNA damage response. The authors propose that SARS-CoV-2, by boosting ribonucleoside triphosphate levels to promote its replication at the expense of dNTPs and by hijacking damage-induced long non-coding RNAs` biology, threatens genome integrity and causes altered DNA damage response activation, induction . . .
  

   

  

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