Using the canine microbiome to bridge translation of cancer immunotherapy from pre-clinical murine models to human clinical trials

HIGHLIGHTS

SUMMARY

    Mouse studies of the microbiome show a large genetic influence which is distinct from humans where and amp;lt;10% of taxa are thought to be heritable. This concern is reinforced by studies which have demonstrated the impact of environmental influences especially diet and drugs, as the most prominent factors influencing the microbiome in humans. Matson et_al and Gopalakrishnan et_al used FMT to study whether human commensal microbes would potentiate anti-tumor T_cell Success and limitations of the murine model Murine models represent the most used model for studying host-microbiome physiology at both . . .

     

    Logo ScioWire Beta black

    If you want to have access to all the content you need to log in!

    Thanks :)

    If you don't have an account, you can create one here.

     

Scroll to Top

Add A Knowledge Base Question !

+ = Verify Human or Spambot ?