Structure and kinase activity of bacterial cell cycle regulator ccrz

HIGHLIGHTS

  • who: Katherine J. Wozniak and colleagues from the Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan have published the paper: Structure and kinase activity of bacterial cell cycle regulator CcrZ, in the Journal: (JOURNAL) of May/16,/2022
  • what: The authors investigate the CcrZ homolog in Bacillus subtilis and show that cells lacking ccrZ are sensitive to a broad range of DNA damage. The authors demonstrate that increased expression of ccrZ results in over-initiation of DNA replication. The authors show that CcrZ interacts with replication initiation proteins DnaA and . . .

     

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