Shared genetic loci and causal relations between schizophrenia and obsessive-compulsive disorder

HIGHLIGHTS

  • who: Yu Chen from the (UNIVERSITY) have published the paper: Shared genetic loci and causal relations between schizophrenia and obsessive-compulsive disorder, in the Journal: (JOURNAL) of 15/03/2023
  • what: The authors investigate if there are genetic loci jointly associated with SCZ and OCD using the cond/conjFDR method. This study identified shared genetic architecture beyond the genetic correlation between SCZ and OCD.
  • how: Last Mendelian randomization results showed that SCZ is a causal risk factor for OCD.
  • future: An affinity between OCD and schizophrenia is supported by many studies . . .

     

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