HIGHLIGHTS
- who: Petra Brugge from the (UNIVERSITY) have published the Article: Homologous recombination deficiency derived from whole-genome sequencing predicts platinum response in triple-negative breast cancers, in the Journal: (JOURNAL) of 14/04/2022
- what: The authors assess the in_vivo response to platinum agents in 55 patient-derived xenografts (PDX) of TNBC to identify determinants of response. The authors studied the response to platinum-based chemotherapy in a large cohort of TNBC PDX models, analysed the predictive value of genomic and functional biomarkers of HRD and identified potential drivers of platinum sensitivity.
- how . . .
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